Entourage Effect 101 & Everything You Need to Know

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If you’ve been around the cannabis world for a while, chances are you’ve heard the term “entourage effect” tossed around. It turns out that phrase is more than just a catchphrase. It points to a real phenomenon backed by genuine scientific interest.

We answer the question “what is the entourage effect” and break down how to spot it in the cannabis products you use. We’ll also suggest a few full-spectrum, terpene-rich products that deliver well-rounded experiences by putting the entourage effect to work.

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Entourage Effect Explained and Its Purpose

The entourage effect in cannabis refers to the different compounds of the cannabis plant working together to achieve balanced effects and a heightened experience through sensory features such as aroma and taste.

The entourage effect can correct the adverse characteristics of too much THC, such as anxiety and paranoia, and add to the overall experience and positive or desired effects.

The Role of Cannabinoids in the Entourage Effect

Cannabinoids such as tetrahydrocannabinol (THC) and cannabidiol (CBD) work with the body’s endocannabinoid system (ECS) by binding to CB1 and CB2 receptors. This interaction with the ECS results in the psychoactive and therapeutic effects. 

Other secondary cannabinoids, such as CBC and CBG, enhance anti-inflammatory and analgesic properties. The direct relationship with the ECS makes cannabinoids the drivers of the entourage effect.

How Terpenes Impact the Entourage Effect

Terpenes are considered the modulators of the entourage effect, playing a central role in how a product ultimately makes you feel. These naturally occurring compounds give plants their aroma and flavor, working the same way they do in food, where a hint of pine or citrus can transform an otherwise flat dish. In cannabis, that same principle applies to the experience itself, shaping it well beyond flavor alone.

Their role in the entourage effect comes down to biology. Terpenes interact directly with the body’s CB1 and CB2 receptors while also increasing cell membrane permeability, allowing cannabinoids to be absorbed more efficiently and work together more effectively.

One of the most popular terpenes, beta-caryophyllene, acts as both a terpene and a cannabinoid as it binds to the CB2 receptors and provides sensory features.

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Full Spectrum Cannabis vs. Isolate Products

If you’re looking for a product with the advantage of the entourage effect, you want to look for something labeled full-spectrum. Full-spectrum THC includes all the naturally occurring compounds, such as other cannabinoids, terpenes, and flavonoids.

Isolates extract just the desired cannabinoid, usually THC or CBD. Since they contain no other cannabinoids or terpenes, you would not benefit from the entourage effect of isolate or distilled products. Isolate products often work better for people who are looking for a higher and purer dose of THC or CBD for a specific condition.

Cannabis oil vape pen cartridges. Alternative method of smoking the THC extracted from marijuana plants.

Entourage-Focused Product Picks

When selecting a product that puts the entourage effect to work, look for multiple cannabinoids alongside a strong, well-rounded terpene profile. Below are some products we recommend:

At Green Choice Dispensary, we’re proud to be part of the Blackstone community, bringing a craft, boutique cannabis experience to an environment that welcomes everyone, from curious first-timers to seasoned connoisseurs. 

Stop by our dispensary and talk with one of our budtenders about what’s on our shelves right now. Can’t make it in person? Reach out to us online anytime; we’re always happy to help!

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